Article
Molecular drug resistance profiles of Mycobacterium tuberculosis from sputum specimens using ion semiconductor sequencing.
Journal of microbiological methods - 1 Feb 2018
Park Joonhong, Jang Woori, Kim Myungshin, Kim Yonggoo, Shin So Youn, Park Kuhn, Kim Myung Sook, Shin Soyoung
Abstract excerpt
The increasing burden of multidrug resistant (MDR)-TB, defined by resistance to rifampin (RFP) and isoniazid (INH), and extensively drug resistant-TB, defined by MDR-TB with additional resistance to fluoroquinolones (FQs) and more than one second-line injectable drug, is a serious impediment to global TB control. We evaluated the feasibility of full-length gene analysis including inhA, katG, rpoB, pncA, rpsL...
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