Article
Utility of the BRAF p.V600E immunoperoxidase stain in FNA direct smears and cell block preparations from patients with thyroid carcinoma.
Cancer cytopathology - 1 Jun 2018
Smith Amber L, Williams Michelle D, Stewart John, Wang Wei-Lien, Krishnamurthy Savitri, Cabanillas Maria E, Roy-Chowdhuri Sinchita
Abstract excerpt
BACKGROUND: The identification of BRAF mutations in thyroid cancer has prognostic and therapeutic implications. Although the gold standard for identifying BRAF mutations is molecular testing, the ability to perform BRAF p.V600E immunostaining on fine-needle aspiration (FNA) samples can facilitate the rapid triaging of patients to treatment options. METHODS: A total of 50 thyroid carcinoma FNA samples, including...
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