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Article

Structural and Functional Neuroimaging of Polygenic Risk for Schizophrenia: A Recall-by-Genotype-Based Approach.

Schizophrenia bulletin - 7 Mar 2019

Lancaster Thomas M, Dimitriadis Stavros L, Tansey Katherine E, Perry Gavin, Ihssen Niklas, Jones Derek K, Singh Krish D, Holmans Peter, Pocklington Andrew, Davey Smith George, Zammit Stan, Hall Jeremy, O'Donovan Michael C, Owen Michael J, Linden David E

Abstract excerpt

Risk profile scores (RPS) derived from genome-wide association studies (GWAS) explain a considerable amount of susceptibility for schizophrenia (SCZ). However, little is known about how common genetic risk factors for SCZ influence the structure and function of the human brain, largely due to the constraints of imaging sample sizes. In the current study, we use a novel recall-by-genotype (RbG) methodological...

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Identifiers

PMID: 29608775
DOI: 10.1093/schbul/sby037
PMCID: PMC6403064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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