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Article

Muscle-restricted nuclear receptor interaction protein knockout causes motor neuron degeneration through down-regulation of myogenin at the neuromuscular junction.

Journal of cachexia, sarcopenia and muscle - 1 Aug 2018

Chen Hsin-Hsiung, Tsai Li-Kai, Liao Kuan-Yu, Wu Tung-Chien, Huang Yun-Hsin, Huang Yuan-Chun, Chang Szu-Wei, Wang Pei-Yu, Tsao Yeou-Ping, Chen Show-Li

Abstract excerpt

BACKGROUND: Nuclear receptor interaction protein (NRIP) is a calcium/calmodulin (CaM) binding protein. Nuclear receptor interaction protein interacts with CaM to activate calcineurin and CaMKII signalling. The conventional NRIP knockout mice (global knockout) showed muscular abnormality with reduction of muscle oxidative functions and motor function defects. METHODS: To investigate the role of NRIP on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29608040
DOI: 10.1002/jcsm.12299
PMCID: PMC6104115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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