Article
Targeted disruption of N-RAP gene function by RNA interference: a role for N-RAP in myofibril organization.
Cell motility and the cytoskeleton - 1 Aug 2006
Dhume Ashwini, Lu Shajia, Horowits Robert
Abstract excerpt
N-RAP is a muscle-specific protein concentrated in myofibril precursors during sarcomere assembly and at intercalated disks in adult heart. We used RNA interference to achieve a targeted decrease in N-RAP transcript and protein levels in primary cultures of embryonic mouse cardiomyocytes. N-RAP t...
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