Article
Mutation screening of the GLIS3 gene in a cohort of 592 Chinese patients with congenital hypothyroidism.
Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2018
Fu Chunyun, Luo Shiyu, Long Xigui, Li Yingfeng, She Shangyang, Hu Xuehua, Mo Meizhen, Wang Zhanghong, Chen Yuhua, He Chun, Su Jiasun, Zhang Yue, Lin Fei, Xie Bobo, Li Qifei, Chen Shaoke
Abstract excerpt
OBJECTIVES: Defects in the human GLI-similar 3 (GLIS3) gene are reported to be a rare cause of congenital hypothyroidism (CH) and neonatal diabetes. The aim of this study was to examine the prevalence of GLIS3 mutation among CH patients in the Guangxi Zhuang Autonomous Region of China and to define the relationships between GLIS3 genotypes and clinical phenotypes. METHODS: Blood samples were collected from 592...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.