Lack of evidence of association between IFNG and IL28B polymorphisms and QuantiFERON-CMV test results in seropositive transplant patients.

doi:10.1016/j.humimm.2018.03.009

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Article

Lack of evidence of association between IFNG and IL28B polymorphisms and QuantiFERON-CMV test results in seropositive transplant patients.

Human immunology - 1 Jun 2018

Aguado Rocío, Páez-Vega Aurora, Agüera María L, Montejo Miguel, Guirado Lluis, Fortún Jesús, Suárez-Benjumea Alejandro, Len Oscar, Fariñas María C, de Gracia Carmen, Hernández Domingo, Cobos-Ceballos María J, Torre-Cisneros Julián, Cantisán Sara

Abstract excerpt

The aim of this study was to analyze the relationship between the IFNG +874 T/A and IL28B (rs12979860) C/T polymorphisms and the secretion of IFNG by CD8+ T cells after stimulation with cytomegalovirus (CMV) peptides, measured using QuantiFERON-CMV (QF-CMV) assay. A total of 184 CMV-seropositive solid organ transplant patients (108 kidney, 68 liver and 8 lung) were recruited. Of them, 151 patients were QF-CMV...

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PMID: 29605690
DOI: 10.1016/j.humimm.2018.03.009

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IFNG

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