Article
IL28B rs12979860 genotype as a predictor marker of progression to BKVirus Associated nephropathy, after kidney transplantation.
Scientific reports - 27 Jul 2017
Dvir Roee, Paloschi Vera, Canducci Filippo, Dell'Antonio Giacomo, Racca Sara, Caldara Rossana, Pantaleo Giuseppe, Clementi Massimo, Secchi Antonio
Abstract excerpt
BK virus (BKV) associated nephropathy (BKVAN) is still an important cause of allograft dysfunction after kidney transplantation (KT). Recent data have shown that the new interferon (IFN)-λ family has been ascribed antiviral properties similar to IFNα, and that the response to IFNλ in kidney is restricted to epithelial cells, suggesting that the IFNλ system evolves as specific protection of the epithelia. We aimed...
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