Article
Validation of cytomegalovirus immune competence assays for the characterization of CD8(+) T cell responses posttransplant.
Clinical & developmental immunology - 1 Jan 2012
Ravkov Eugene V, Pavlov Igor Y, Hanson Kimberly E, Delgado Julio C
Abstract excerpt
Cytomegalovirus (CMV) infection is one of the most important infectious complications of transplantation. Monitoring CMV-specific CD8 T cell immunity is useful for predicting active CMV infection and for directing targeted antiviral therapy. In this study, we examined four basic parameters for validation of CMV-specific tetramer staining and peptide stimulation assays that cover five most frequent HLA class I...
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