Article
Impact of IFN lambda 3/4 single nucleotide polymorphisms on the cytomegalovirus reactivation in autologous stem cell transplant patients.
PloS one - 1 Jan 2018
Annibali Ombretta, Piccioni Livia, Tomarchio Valeria, Circhetta Erika, Sarlo Chiara, Franceschini Luca, Cantonetti Maria, Rizzo Emanuela, Angeletti Silvia, Tirindelli Maria Cristina, Scagnolari Carolina, Statzu Maura, Avvisati Giuseppe, Riva Elisabetta
Abstract excerpt
Cytomegalovirus (CMV) infection represents one of the main cause mortality after Stem Cell Transplantation. Recently, a protective effect of the T allele of rs12979860 IL28B Single Nucleotide Polymorphisms (SNPs) against CMV infection in the allogenic stem cell transplantation was suggested. We investigate whether the rs12979860 IL28B SNP and the relative rs368234815 (IFNλ4) genotype may affect the incidence of...
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