Article
Independent development of endometrial epithelium and stroma within the same endometriosis.
The Journal of pathology - 1 Jul 2018
Noë Michaël, Ayhan Ayse, Wang Tian-Li, Shih Ie-Ming
Abstract excerpt
The pathogenesis of endometriosis, a common benign but debilitating disease in women, remains elusive. The currently held stem cell theory posits that circulating progenitor/stem cells are deposited outside the uterus, where they differentiate into endometrial stroma and glandular tissue to establish endometriosis. Fundamental to testing this hypothesis is to elucidate the evolution of both tissue types. Here, we...
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