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Rethinking the pathogenesis of endometriosis: Complex interactions of genomic, epigenetic, and environmental factors

18 Sept 2024

Abstract excerpt

AIM: Endometriosis is a complex, multifactorial disease. Recent advances in molecular biology underscore that somatic mutations within the epithelial component of the normal endometrium, alongside aberrant epigenetic alterations within endometrial stromal cells, may serve as stimulators for the proliferation of endometriotic tissue within the peritoneal cavity. Nevertheless, pivotal inquiries persist: the...

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PMID: 39293995
DOI: 10.1111/jog.16089

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