Article
Cancer-associated mutations in endometriosis: shedding light on the pathogenesis and pathophysiology.
Human reproduction update - 15 Apr 2020
Guo Sun-Wei
Abstract excerpt
BACKGROUND: Endometriosis is a benign gynaecological disease. Thus, it came as a complete surprise when it was reported recently that the majority of deep endometriosis lesions harbour somatic mutations and a sizeable portion of them contain known cancer-associated mutations (CAMs). Four more studies have since been published, all demonstrating the existence of CAMs in different subtypes of endometriosis. While...
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