Article
Molecular analysis suggests oligoclonality and metastasis of endometriosis lesions across anatomically defined subtypes.
Fertility and sterility - 1 Sept 2022
Praetorius Teresa H, Leonova Anna, Lac Vivian, Senz Janine, Tessier-Cloutier Basile, Nazeran Tayyebeh M, Köbel Martin, Grube Marcel, Kraemer Bernhard, Yong Paul J, Kommoss Stefan, Anglesio Michael S
Abstract excerpt
OBJECTIVE: To investigate the heterogeneity of somatic cancer-driver mutations within patients and across endometriosis types. DESIGN: A single-center cohort, retrospective study. SETTING: Tertiary specialist-care center at a university hospital. PATIENT(S): Patients with surgically and histologically confirmed endometriosis of at least 2 anatomically distinct types (ovarian, deep infiltrating, and superficial)....
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