Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Calcimimetics increase CaSR expression and reduce mineralization in vascular smooth muscle cells: mechanisms of action.

Cardiovascular research - 1 Feb 2014

Hénaut Lucie, Boudot Cédric, Massy Ziad A, Lopez-Fernandez Irene, Dupont Sebastien, Mary Aurélien, Drüeke Tilman B, Kamel Saïd, Brazier Michel, Mentaverri Romuald

Abstract excerpt

AIMS: Vascular calcification (VC) contributes to morbidity and mortality in patients with chronic kidney disease (CKD). Allosteric modulators of the calcium (Ca)-sensing receptor (CaSR) may slow the progression of VC in CKD patients either by reducing serum parathyroid hormone (PTH), Ca, and phosphate levels or by a direct effect on the vessel wall. The aim of this study was to examine the effects of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aniline Compounds
Share to Biphenyl Compounds

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Collagen Type I

Share to Endoplasmic Reticulum

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Receptors, Calcium-Sensing

Share to Vascular Calcification

Source

Identifiers

PMID: 24217682
DOI: 10.1093/cvr/cvt249

Genes

PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Calcimimetics increase CaSR expression and reduce mineralization in vascular smooth muscle cells: mechanisms of action.PMID 24217682Read ↗

Key regulators of vascular calcification in chronic kidney disease: Hyperphosphatemia, BMP2, and RUNX2Semantic proximity Read ↗

The molecular biology and pathophysiology of vascular calcification.Semantic proximity Read ↗

Epidermal Growth Factor Receptor Inhibition Prevents Caveolin-1-dependent Calcifying Extracellular Vesicle BiogenesisSemantic proximity Read ↗

Vascular calcification in CKD: New insights into its mechanismsSemantic proximity Read ↗

Modulation and action of the calcium-sensing receptor.Semantic proximity Read ↗

Magnesium Counteracts Vascular Calcification: Passive Interference or Active Modulation?Semantic proximity Read ↗

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness.Semantic proximity Read ↗

The role of the calcium-sensing receptor in disorders of abnormal calcium handling and cardiovascular disease.Semantic proximity Read ↗

Intermedin inhibits vascular calcification by increasing the level of matrix gamma-carboxyglutamic acid protein.Semantic proximity Read ↗

Arterial Stiffness: A Focus on Vascular Calcification and Its Link to Bone Mineralization.Semantic proximity Read ↗

Restoration of microRNA‐30b expression alleviates vascular calcification through the mTOR signaling pathway and autophagySemantic proximity Read ↗

MicroRNAs that target Ca2+ transporters are involved in vascular smooth muscle cell calcificationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.