Article
Bone morphogenetic proteins in vascular calcification.
Circulation research - 22 Jul 2005
Hruska Keith A, Mathew Suresh, Saab Georges
Abstract excerpt
Vascular calcification is a common problem among the elderly and those with chronic kidney disease (CKD) and diabetes. The process of tunica media vascular calcification in CKD appears to involve a phenotypic change in the vascular smooth muscle cell (VSMC) resulting in cell-mediated mineralization of the extracellular matrix. The bone morphogenetic proteins (BMPs) are important regulators in orthotopic bone...
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