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Article

Phosphatidylserine liposomes mimic apoptotic cells to attenuate atherosclerosis by expanding polyreactive IgM producing B1a lymphocytes.

Cardiovascular research - 1 Jun 2015

Hosseini Hamid, Li Yi, Kanellakis Peter, Tay Christopher, Cao Anh, Tipping Peter, Bobik Alex, Toh Ban-Hock, Kyaw Tin

Abstract excerpt

AIMS: To investigate whether activation of atheroprotective peritoneal B1a cells by apoptotic cells or phosphatidylserine liposomes (PSLs) can enhance their protective actions during atherosclerosis development. METHODS AND RESULTS: Male apolipoprotein E-knockout (ApoE-/-) mice were treated with apoptotic cells or PSLs at the beginning of 8-week high-fat diet. Intraperitoneally administered apoptotic cells...

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Identifiers

PMID: 25681396
DOI: 10.1093/cvr/cvv037

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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