Article
The landscape of viral associations in human cancers.
Nature genetics - 1 Mar 2020
Zapatka Marc, Borozan Ivan, Brewer Daniel S, Iskar Murat, Grundhoff Adam, Alawi Malik, Desai Nikita, Sültmann Holger, Moch Holger, Cooper Colin S, Eils Roland, Ferretti Vincent, Lichter Peter
Abstract excerpt
Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for which whole-genome and-for a subset-whole-transcriptome sequencing data from 2,658 cancers across 38 tumor types was aggregated, we systematically investigated potential viral pathogens using a consensus approach that integrated three independent pipelines. Viruses were detected in 382 genome and 68 transcriptome datasets. We found...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
