Article

Super-pangenome analysis of 3562 human and animal papillomavirus isolates illuminates their genome and pathogenicity evolution

2025-07-21

Abstract excerpt

Papillomaviruses (PVs) are groups of ubiquitous DNA viruses infecting a wide range of vertebrate hosts, including human. The infection of some human PVs (i.e., HPVs) are strongly associated with cancers, but it remains elusive how such pathogenicity evolved at the genomic level. Here we performed a super-pangenome analysis on a compendium of well-curated 3562 human and animal PV genomes. We found their global geno...

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Literature Corpus work: 6fbf9e89-63ca-5b09-be98-616ecdfb4e7f
DOI: 10.1101/2025.07.20.664904

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