Article
Simulating variance heterogeneity in quantitative genome wide association studies.
BMC bioinformatics - 21 Mar 2018
Al Kawam Ahmad, Alshawaqfeh Mustafa, Cai James J, Serpedin Erchin, Datta Aniruddha
Abstract excerpt
BACKGROUND: Analyzing Variance heterogeneity in genome wide association studies (vGWAS) is an emerging approach for detecting genetic loci involved in gene-gene and gene-environment interactions. vGWAS analysis detects variability in phenotype values across genotypes, as opposed to typical GWAS analysis, which detects variations in the mean phenotype value. RESULTS: A handful of vGWAS analysis methods have been...
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