Reverting doxorubicin resistance in colon cancer by targeting a key signaling protein, steroid receptor coactivator

Abstract excerpt

Although there have been notable improvements in treatments against cancer, further research is required. In colon cancer, nearly all patients eventually experience drug resistance and stop responding to the approved drugs, making treatment difficult. Steroid receptor coactivator (SRC) is an oncogenic nuclear receptor coactivator that serves an important role in drug resistance. The present study generated a...

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