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Article

Molecular features of doxorubicin-resistance development in colorectal cancer CX-1 cell line

1 Jan 2016

Abstract excerpt

BACKGROUND AND AIM: Resistance to chemotherapy is the key obstacle to the effective treatment of various cancers. Accumulating evidence suggests significant involvement of the epithelial-to-mesenchymal transition (EMT) in the chemoresistance of most cancer types. This study aimed at analyzing the gene expression profile of doxorubicin (DOX)-resistant colorectal cancer cells CX-1. MATERIALS AND METHODS:...

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PMID: 27746118
DOI: 10.1016/j.medici.2016.09.003

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