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Article

Function of insulin‑like growth factor 1 receptor in cancer resistance to chemotherapy (Review)

26 Oct 2017

Abstract excerpt

Drug resistance is a primary cause of chemotherapeutic failure; however, how this resistance develops is complex. A comprehensive understanding of chemotherapeutic resistance mechanisms may aid in identifying more effective drugs and improve the survival rates of patients with cancer. Insulin‑like growth factor 1 receptor (IGF1R), a member of the insulin receptor family, has been extensively assessed for...

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PMID: 29285186
DOI: 10.3892/ol.2017.7276

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