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Article

Role of ASIC1a in Aβ-induced synaptic alterations in the hippocampus.

Pharmacological research - 1 May 2018

Mango D, Nisticò R

Abstract excerpt

Acid-sensing ion channels (ASICs) are widely expressed in the mammalian central nervous system where they play a key role in synaptic transmission and in specific forms of memory. On the other hand, ASICs can be persistently active under pathological conditions contributing to neuronal damage in ischemic stroke, brain trauma, epilepsy and Parkinson's disease. However, to date no experimental evidence has linked...

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Identifiers

PMID: 29574226
DOI: 10.1016/j.phrs.2018.03.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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