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Liquid biopsy by NGS : differential presence of exons ( DPE ) in cell‐free DNA reveals different patterns in metastatic and nonmetastatic colorectal cancer

23 Mar 2018

Abstract excerpt

Next-generation sequencing (NGS) has been proposed as a suitable tool for liquid biopsy in colorectal cancer (CRC), although most studies to date have focused almost exclusively on sequencing of panels of potential clinically actionable genes. We evaluated the clinical value of whole-exome sequencing (WES) of cell-free DNA (cfDNA) circulating in plasma, with the goal of identifying differential clinical profiles...

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PMID: 29573240
DOI: 10.1002/cam4.1399

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