Liquid Biopsies Using Plasma Exosomal Nucleic Acids and Plasma Cell-Free DNA Compared with Clinical Outcomes of Patients with Advanced Cancers.

doi:10.1158/1078-0432.CCR-17-2007

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Article

Liquid Biopsies Using Plasma Exosomal Nucleic Acids and Plasma Cell-Free DNA Compared with Clinical Outcomes of Patients with Advanced Cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2018

Möhrmann Lino, Huang Helen J, Hong David S, Tsimberidou Apostolia M, Fu Siqing, Piha-Paul Sarina A, Subbiah Vivek, Karp Daniel D, Naing Aung, Krug Anne, Enderle Daniel, Priewasser Tina, Noerholm Mikkel, Eitan Erez, Coticchia Christine, Stoll Georg, Jordan Lisa-Marie, Eng Cathy, Kopetz E Scott, Skog Johan, Meric-Bernstam Funda, Janku Filip

Abstract excerpt

Purpose: Blood-based liquid biopsies offer easy access to genomic material for molecular diagnostics in cancer. Commonly used cell-free DNA (cfDNA) originates from dying cells. Exosomal nucleic acids (exoNAs) originate from living cells, which can better reflect underlying cancer biology.Experimental Design: Next-generation sequencing (NGS) was used to test exoNA, and droplet digital PCR (ddPCR) and BEAMing PCR...

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Identifiers

PMID: 29051321
DOI: 10.1158/1078-0432.CCR-17-2007
PMCID: PMC5754253

Genes

MAF
BRAF
EGFR
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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