The Molecular Pathology of Hereditary Cystatin C Amyloid Angiopathy Causing Brain Hemorrhage

Abstract excerpt

Knowledge about molecular pathology of hereditary cystatin C amyloid angiopathy (HCCAA), also called hereditary cerebral hemorrhage with amyloidosis, Icelandic type, has increased greatly in the last decade. The disorder has an autosomal dominant mode of inheritance and causes fatal brain hemorrhage in normotensive young adults. It is due to a mutation in the gene encoding the cysteine proteinase inhibitor,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alzheimer's disease research and treatments
• Share to Amyloidosis: Diagnosis, Treatment, Outcomes
• Share to Iron Metabolism and Disorders