Article
Growth differentiation factor 15 contributes to marrow adipocyte remodeling in response to the growth of leukemic cells
22 Mar 2018
Abstract excerpt
BACKGROUND: The adipocyte remodeling, including of the morphological change, might indicate special pathological function. Our previous study found that the morphological remodeling of larger marrow adipocytes into small marrow adipocytes correlates with a poor prognosis for acute myeloid leukemia (AML) patients. However, the mechanisms contributed to the marrow adipocyte remodeling are still poorly understood....
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