Article
Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.
Acta neuropathologica - 1 Aug 2018
Reinhardt Annekathrin, Stichel Damian, Schrimpf Daniel, Sahm Felix, Korshunov Andrey, Reuss David E, Koelsche Christian, Huang Kristin, Wefers Annika K, Hovestadt Volker, Sill Martin, Gramatzki Dorothee, Felsberg Joerg, Reifenberger Guido, Koch Arend, Thomale Ulrich-W, Becker Albert, Hans Volkmar H, Prinz Marco, Staszewski Ori, Acker Till, Dohmen Hildegard, Hartmann Christian, Mueller Wolf, Tuffaha Muin S A, Paulus Werner, Heß Katharina, Brokinkel Benjamin, Schittenhelm Jens, Monoranu Camelia-Maria, Kessler Almuth Friederike, Loehr Mario, Buslei Rolf, Deckert Martina, Mawrin Christian, Kohlhof Patricia, Hewer Ekkehard, Olar Adriana, Rodriguez Fausto J, Giannini Caterina, NageswaraRao Amulya A, Tabori Uri, Nunes Nuno Miguel, Weller Michael, Pohl Ute, Jaunmuktane Zane, Brandner Sebastian, Unterberg Andreas, Hänggi Daniel, Platten Michael, Pfister Stefan M, Wick Wolfgang, Herold-Mende Christel, Jones David T W, von Deimling Andreas, Capper David
Abstract excerpt
Tumors with histological features of pilocytic astrocytoma (PA), but with increased mitotic activity and additional high-grade features (particularly microvascular proliferation and palisading necrosis) have often been designated anaplastic pilocytic astrocytomas. The status of these tumors as a separate entity has not yet been conclusively demonstrated and molecular features have only been partially...
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