Article
The utility of DNA methylation analysis in elderly patients with pilocytic astrocytoma morphology.
Journal of neuro-oncology - 1 Oct 2022
Suruga Yasuki, Satomi Kaishi, Otani Yoshihiro, Fujii Kentaro, Ishida Joji, Uneda Atsuhito, Tsuboi Nobushige, Makino Keigo, Hirano Shuichiro, Kemmotsu Naoya, Imoto Ryoji, Mizuta Ryo, Tomita Yusuke, Yasuhara Takao, Washio Kana, Yanai Hiroyuki, Matsushita Yuko, Hibiya Yuko, Yoshida Akihiko, Capper David, Ichimura Koichi, Date Isao
Abstract excerpt
PURPOSE: Pilocytic astrocytoma (PA) is a circumscribed low-grade astrocytic glioma, generally considered to be associated with a good prognosis. However, a subset of PA patients shows unfavorable outcomes. In this study, we retrospectively reviewed PA patients and performed further molecular analysis, such as DNA methylation profiling, to identify prognostic factors. METHODS: We analyzed 29...
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