Article
Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1
9 Aug 2022
Abstract excerpt
Gliomas arising in the setting of neurofibromatosis type 1 (NF1) are heterogeneous, occurring from childhood through adulthood, can be histologically low-grade or high-grade, and follow an indolent or aggressive clinical course. Comprehensive profiling of genetic alterations beyond NF1 inactivation and epigenetic classification of these tumors remain limited. Through next-generation sequencing, copy number...
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