Article
High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13.
Acta neuropathologica - 1 Mar 2022
Pratt Drew, Abdullaev Zied, Papanicolau-Sengos Antonios, Ketchum Courtney, Panneer Selvam Pavalan, Chung Hye-Jung, Lee Ina, Raffeld Mark, Gilbert Mark R, Armstrong Terri S, Pytel Peter, Borys Ewa, Klonoski Joshua M, McCord Matthew, Horbinski Craig, Brat Daniel, Perry Arie, Solomon David, Eberhart Charles, Giannini Caterina, Quezado Martha, Aldape Kenneth
Abstract excerpt
Tumors of the central nervous system (CNS) often display a wide morphologic spectrum that has, until recently, been the sole basis for tumor classification. The introduction of the integrated histomolecular diagnostic approach in CNS tumors has facilitated a classification system that is increasingly data-driven and with improved alignment to clinical outcome. Here, we report a previously uncharacterized glioma...
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