Article
TIM family of genes in immunity and tolerance.
Advances in immunology - 1 Jan 2006
Kuchroo Vijay K, Meyers Jennifer Hartt, Umetsu Dale T, DeKruyff Rosemarie H
Abstract excerpt
T cells on activation differentiate into different subsets (Th1 or Th2) with distinct effector functions. These T cell subsets are primarily differentiated on the basis of the cytokines that they produce, however, we have identified a novel gene family called TIM (T cell, immunoglobulin, mucin domain-containing molecules), whose members are differentially expressed on Th1 and Th2 cells. Three of the family...
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