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Article

Characterization of a murine model of non-lethal, symptomatic dengue virus infection.

Scientific reports - 20 Mar 2018

Sarathy Vanessa V, White Mellodee, Li Li, Kaiser Jaclyn A, Campbell Gerald A, Milligan Gregg N, Bourne Nigel, Barrett Alan D T

Abstract excerpt

The mosquito-borne disease dengue is caused by four serologically- and genetically-related viruses, termed DENV-1 to DENV-4. Historical setbacks due to lack of human-like mouse models of dengue were partially remedied with characterization of lethal DENV-2 infection in immunocompromised AG129 mice (deficient in IFN-α/β/γ receptors). Recently, our group established lethal AG129 mouse infection models of DENV-1,...

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Identifiers

PMID: 29559699
DOI: 10.1038/s41598-018-22618-w
PMCID: PMC5861036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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