Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Murine Model for Dengue Virus-Induced Lethal Disease with IncreasedVascular Permeability

27 Sept 2006

Abstract excerpt

Lack of an appropriate animal model for dengue virus (DEN), which causes dengue fever and dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), has impeded characterization of the mechanisms underlying the disease pathogenesis. The cardinal feature of DHF/DSS, the severe form of DEN infection, is increased vascular permeability. To develop a murine model that is more relevant to DHF/DSS, a novel DEN strain,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Malaria Research and Control
Share to Mosquito-borne diseases and control
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17005698
DOI: 10.1128/jvi.00062-06

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Murine Model for Dengue Virus-Induced Lethal Disease with IncreasedVascular PermeabilityPMID 17005698Read ↗

A mouse-passaged dengue virus strain with reduced affinity for heparan sulfate causes severe disease in mice by establishing increased systemic viral loads.Semantic proximity Read ↗

Characterization of a model of lethal dengue virus 2 infection in C57BL/6 mice deficient in the alpha/beta interferon receptor.Semantic proximity Read ↗

A Single Amino Acid in Nonstructural Protein NS4B Confers Virulence to Dengue Virus in AG129 Mice through Enhancement of Viral RNA SynthesisSemantic proximity Read ↗

Aggressive organ penetration and high vector transmissibility of epidemic dengue virus-2 Cosmopolitan genotype in a transmission mouse model.Semantic proximity Read ↗

Delta (B1.617.2) variant of SARS-CoV-2 induces severe neurotropic patterns in K18-hACE2 miceSemantic proximity Read ↗

Tracking the evolution of dengue virus strains D2S10 and D2S20 by 454 pyrosequencing.Semantic proximity Read ↗

First Experimental In Vivo Model of Enhanced Dengue Disease Severity through Maternally Acquired Heterotypic Dengue AntibodiesSemantic proximity Read ↗

Higher‐temperature‐adapted dengue virus serotype 2 strain exhibits enhanced virulence in AG129 mouse modelSemantic proximity Read ↗

SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 miceSemantic proximity Read ↗

Brain transcriptomics reveals features of the host response after dengue virus type I infection induced central nervous system injury in AGB6 miceSemantic proximity Read ↗

Advances and new insights in the neuropathogenesis of dengue infection.Semantic proximity Read ↗

Sequence diversity of dengue virus type 2 in brain and thymus of infected interferon receptor ko mice: implications for dengue virulence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.