Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DA virus mutant H101 has altered CNS pathogenesis and causes immunosuppression.

Journal of neuroimmunology - 15 Dec 2014

Cusick Matthew F, Libbey Jane E, Doty Daniel J, Fujinami Robert S

Abstract excerpt

Viruses use various mechanisms to evade clearance by the host. Investigating how a few changes in the genome of a non-lethal virus can lead to altered disease, from survivable to immunosuppression/death, would provide valuable information into viral pathogenesis. The Daniels strain of Theiler's murine encephalomyelitis virus causes an asymptomatic infection or acute encephalitis followed by viral clearance. A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Concanavalin A
Share to Encephalomyelitis, Autoimmune, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunosuppression Therapy

Share to Myelin Proteolipid Protein

Share to Peptide Fragments

Share to Phycocyanin

Share to Spleen

Share to Theilovirus

Source

Open in PubMed Open full text

Identifiers

PMID: 25468274
DOI: 10.1016/j.jneuroim.2014.10.012
PMCID: PMC4314319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DA virus mutant H101 has altered CNS pathogenesis and causes immunosuppression.PMID 25468274Read ↗

Mapping Attenuation Determinants in Enterovirus-D68Semantic proximity Read ↗

A single amino acid mutation in norovirus NS4 promotes viral spread.Semantic proximity Read ↗

Hydrocephalus in mice infected with a Theiler's murine encephalomyelitis virus variant.Semantic proximity Read ↗

Determinants of persistence and demyelination of the DA strain of Theiler's virus are found only in the VP1 gene.Semantic proximity Read ↗

Emerging Infections of CNS : Avian Influenza A Virus, R ift V alley Fever Virus and Human ParechovirusSemantic proximity Read ↗

Investigation of Powassan virus lineage II pathogenesis and neurotropism in miceSemantic proximity Read ↗

Lethality of West Nile virus strains in a mouse modelSemantic proximity Read ↗

Direct evidence of a role for amino acid 101 of VP-1 in central nervous system disease in Theiler's murine encephalomyelitis virus infectionSemantic proximity Read ↗

Delta (B1.617.2) variant of SARS-CoV-2 induces severe neurotropic patterns in K18-hACE2 miceSemantic proximity Read ↗

A Single Amino Acid in Nonstructural Protein NS4B Confers Virulence to Dengue Virus in AG129 Mice through Enhancement of Viral RNA SynthesisSemantic proximity Read ↗

Norovirus evolution in immunodeficient mice reveals potentiated pathogenicity via a single nucleotide change in the viral capsid.Semantic proximity Read ↗

Murine Model for Dengue Virus-Induced Lethal Disease with IncreasedVascular PermeabilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.