Article
Detection of drug-resistant malaria in resource-limited settings: efficient and high-throughput surveillance of artemisinin and partner drug resistance.
The Journal of antimicrobial chemotherapy - 3 Jun 2024
Fukuda Naoyuki, Yoshida Naoko, Balikagala Betty, Tsuru Ibuki, Ikeda Mie, Hirai Makoto, Anywar Denis A, Odongo-Aginya Emannuel I, Mita Toshihiro
Abstract excerpt
OBJECTIVES: Artemisinin-resistant Plasmodium falciparum malaria is currently spreading globally, including in Africa. Artemisinin resistance also leads to resistance to partner drugs used in artemisinin-based combination therapies. Sequencing of kelch13, which is associated with artemisinin resistance, culture-based partner drug susceptibility tests, and ELISA-based growth measurement are conventionally used to...
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