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Article

N-palmitoylethanolamide Prevents Parkinsonian Phenotypes in Aged Mice.

Molecular neurobiology - 1 Nov 2018

Crupi Rosalia, Impellizzeri Daniela, Cordaro Marika, Siracusa Rosalba, Casili Giovanna, Evangelista Maurizio, Cuzzocrea Salvatore

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative disease characterized by degeneration of dopaminergic neurons. Aging is a major risk factor for idiopathic PD. Several prior studies examined the neuroprotective effects of palmitoylethanolamide (PEA), alone or combined with antioxidants, in a model of PD induced by the dopaminergic toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Here, we analyzed the...

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PMID: 29552727
DOI: 10.1007/s12035-018-0959-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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