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Integrative lipidomics of brain and plasma uncovers sex-specific metabolic signatures in Parkinson’s disease

2025-10-03

Abstract excerpt

Lipid dysregulation is increasingly recognized as a key feature of Parkinson’s disease (PD). A central unresolved question, however, is whether lipidomic signatures identified in accessible peripheral biofluids faithfully recapitulate the pathogenic alterations within the central nervous system (CNS). This gap impedes the development of reliable biomarkers and constrains a comprehensive understanding of PD pathoph...

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Literature Corpus work
1420896e-8555-5ce7-be2c-52f16802573a
DOI
10.1101/2025.10.02.679990
Open publication

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Integrative lipidomics of brain and plasma uncovers sex-specific metabolic signatures in Parkinson’s diseaseDOI 10.1101/2025.10.02.679990
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