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Article

Apolipoprotein E genotypes and longevity across dementia disorders.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jul 2018

Skillbäck Tobias, Lautner Ronald, Mattsson Niklas, Schott Jonathan M, Skoog Ingmar, Nägga Katarina, Kilander Lena, Wimo Anders, Winblad Bengt, Eriksdotter Maria, Blennow Kaj, Zetterberg Henrik

Abstract excerpt

INTRODUCTION: The ε4 allele of the apolipoprotein E (APOE) gene is a prominent risk factor for Alzheimer's disease (AD), but its implication in other dementias is less well studied. METHODS: We used a data set on 2858 subjects (1098 AD, 260 vascular dementia [VaD], 145 mixed AD and VaD, 90 other dementia diagnoses, and 1265 controls) to examine the association of APOE polymorphisms with clinical dementia...

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Identifiers

PMID: 29548722
DOI: 10.1016/j.jalz.2018.02.003

Genes

APOE

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