Serum apolipoprotein E is associated with long-term risk of Alzheimer's disease: The Rotterdam Study.

doi:10.1016/j.neulet.2016.02.018

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Article

Serum apolipoprotein E is associated with long-term risk of Alzheimer's disease: The Rotterdam Study.

Neuroscience letters - 23 Mar 2016

Wolters Frank J, Koudstaal Peter J, Hofman Albert, van Duijn Cornelia M, Ikram M Arfan

Abstract excerpt

BACKGROUND: Serum levels of apolipoprotein E (apoE) have been suggested as potential biomarker for dementia, but the long-term association between apoE and risk of dementia is uncertain. METHODS: Between 1990 and 1993, we measured serum apoE by immunoassay in 1042 non-demented individuals (mean ± SD age 68.4 ± 7.3 years; 59.3% women) from the population-based Rotterdam Study. Follow-up for dementia was complete...

Topics

Aged
Alzheimer Disease
Apolipoproteins E
Female
Genotype
Humans
Male
Middle Aged
Risk Assessment

Source

Open in PubMed

Identifiers

PMID: 26876448
DOI: 10.1016/j.neulet.2016.02.018

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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