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Article

High-Pressure NMR and SAXS Reveals How Capping Modulates Folding Cooperativity of the pp32 Leucine-rich Repeat Protein.

Journal of molecular biology - 27 Apr 2018

Zhang Yi, Berghaus Melanie, Klein Sean, Jenkins Kelly, Zhang Siwen, McCallum Scott A, Morgan Joel E, Winter Roland, Barrick Doug, Royer Catherine A

Abstract excerpt

Many repeat proteins contain capping motifs, which serve to shield the hydrophobic core from solvent and maintain structural integrity. While the role of capping motifs in enhancing the stability and structural integrity of repeat proteins is well documented, their contribution to folding cooperativity is not. Here we examined the role of capping motifs in defining the folding cooperativity of the leucine-rich...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29545082
DOI: 10.1016/j.jmb.2018.03.005
PMCID: PMC13216746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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