Article
Structural and Functional Insights into Bacillus subtilis Sigma Factor Inhibitor, CsfB.
Structure (London, England : 1993) - 3 Apr 2018
Martínez-Lumbreras Santiago, Alfano Caterina, Evans Nicola J, Collins Katherine M, Flanagan Kelly A, Atkinson R Andrew, Krysztofinska Ewelina M, Vydyanath Anupama, Jackter Jacquelin, Fixon-Owoo Sarah, Camp Amy H, Isaacson Rivka L
Abstract excerpt
Global changes in bacterial gene expression can be orchestrated by the coordinated activation/deactivation of alternative sigma (σ) factor subunits of RNA polymerase. Sigma factors themselves are regulated in myriad ways, including via anti-sigma factors. Here, we have determined the solution structure of anti-sigma factor CsfB, responsible for inhibition of two alternative sigma factors, σG and σE, during spore...
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