Genetic dissection of an inhibitor of the sporulation sigma factor sigma(G).

Abstract excerpt

Sporulation in Bacillus subtilis is controlled by a cascade of four sigma factors that are held into inactive form until the proper stage of development. The Gin protein, encoded by csfB, is able to strongly inhibit the activity of one of these factors, sigma(G), in vivo. The csfB gene is present in a large number of endospore formers, but the various Gin orthologues show little conservation, in striking contrast...

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