Article
The membrane transporter PotE is required for virulence in avian pathogenic Escherichia coli (APEC).
Veterinary microbiology - 1 Mar 2018
Guerra Priscila Regina, Herrero-Fresno Ana, Pors Susanne Elisabeth, Ahmed Shahana, Wang Dan, Thøfner Ida, Antenucci Fabio, Olsen John Elmerdahl
Abstract excerpt
Over the last few years, polyamines have been described as key-signal of virulence in pathogenic bacteria. In the current study, we investigated whether the knockout of genes related to polyamine biosynthesis and putrescine transport affected the virulence of an avian pathogenic E. coli (APEC) strain. One-week-old White Leghorn chickens were infected intratracheally with mutants in polyamine biosynthesis (ΔspeB/C...
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