Article
Signature-tagged mutagenesis in a chicken infection model leads to the identification of a novel avian pathogenic Escherichia coli fimbrial adhesin.
PloS one - 12 Nov 2009
Antão Esther-Maria, Ewers Christa, Gürlebeck Doreen, Preisinger Rudolf, Homeier Timo, Li Ganwu, Wieler Lothar H
Abstract excerpt
The extraintestinal pathogen, avian pathogenic E. coli (APEC), known to cause systemic infections in chickens, is responsible for large economic losses in the poultry industry worldwide. In order to identify genes involved in the early essential stages of pathogenesis, namely adhesion and coloniz...
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