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Article

Polyamines are required for virulence in Salmonella enterica serovar Typhimurium.

PloS one - 1 Jan 2012

Jelsbak Lotte, Thomsen Line Elnif, Wallrodt Inke, Jensen Peter Ruhdal, Olsen John Elmerdahl

Abstract excerpt

Sensing and responding to environmental cues is a fundamental characteristic of bacterial physiology and virulence. Here we identify polyamines as novel environmental signals essential for virulence of Salmonella enterica serovar Typhimurium, a major intracellular pathogen and a model organism for studying typhoid fever. Central to its virulence are two major virulence loci Salmonella Pathogenicity Island 1 and 2...

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Source

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Identifiers

PMID: 22558361
DOI: 10.1371/journal.pone.0036149
PMCID: PMC3340349

Genes

SPI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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