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Article

T Cell Phenotype and T Cell Receptor Repertoire in Patients with Major Depressive Disorder.

Frontiers in immunology - 1 Jan 2018

Patas Kostas, Willing Anne, Demiralay Cüneyt, Engler Jan Broder, Lupu Andreea, Ramien Caren, Schäfer Tobias, Gach Christian, Stumm Laura, Chan Kenneth, Vignali Marissa, Arck Petra C, Friese Manuel A, Pless Ole, Wiedemann Klaus, Agorastos Agorastos, Gold Stefan M

Abstract excerpt

While a link between inflammation and the development of neuropsychiatric disorders, including major depressive disorder (MDD) is supported by a growing body of evidence, little is known about the contribution of aberrant adaptive immunity in this context. Here, we conducted in-depth characterization of T cell phenotype and T cell receptor (TCR) repertoire in MDD. For this cross-sectional case-control study, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29515587
DOI: 10.3389/fimmu.2018.00291
PMCID: PMC5826233

Genes

CCR6
CXCR3
FOXP3

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