Article

Immune System Alterations in Depression across Baseline and Flu Vaccine Challenge

2025-12-05

Abstract excerpt

<h4>ABSTRACT</h4> There are multiple reports of elevated inflammation in patients with major depression. It is, however, unclear whether these reported perturbations in immune functions in depression affect the general functionality of the peripheral immune system. Here, using single-cell RNAsequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs) extracted from blood samples collected prior to a flu...

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Literature Corpus work: 8b6804f0-b415-5a7c-af65-c5d6d4efae6d
DOI: 10.64898/2025.12.02.691874

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