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Monocyte Dysregulation Defines an MDD-Specific Transcriptional Signature Closely Linked to Clinical MDD Traits

2025-08-15

Abstract excerpt

<h4>Objective</h4> Major depressive disorder (MDD) is a highly heterogeneous psychiatric condition contributing significantly to the global disease burden. In a subset of MDD patients inflammatory processes accompany the disease and this has also been reported for other psychiatric conditions like schizophrenia (SZ). However, little is known regarding immune deregulation in relation to clinical symptoms. <h4>Meth...

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Literature Corpus work
effc29d5-444c-528a-9423-c53e273d08ca
DOI
10.1101/2025.08.12.669833
Open publication

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Monocyte Dysregulation Defines an MDD-Specific Transcriptional Signature Closely Linked to Clinical MDD TraitsDOI 10.1101/2025.08.12.669833
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